Samylin ® Samylin

Samylin ®

Samylin has a unique formulation which promotes optimal liver health. Provided in a complete range of breed-size specific tablets and sachets, its unique ingredients help to aid liver function and neutralise free radicals.

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Why Samylin?

Samylin is made to a trusted formula to support the liver in a range of functions, for example to support the liver when it is processing medication.

Why Should I See My Vet?

At VetPlus we believe vets are best placed to advise on the right course of action for your pet. You know your pet better than anyone and will be able to pick up on subtle changes in them. We recommend taking this knowledge to your vet if you suspect there may be something wrong.

What Else Can I Do?

There are many things you can do to help keep your pets liver healthy. For example maintain a healthy diet, exercise regime and lifestyle. Speak to your vet for advice.

Feeding Guidelines

Feeding Guidelines

Samylin comes in either sachets or tablets. Your vet may advise you which is better for your pet, or you may find your pet prefers one over the other.

Tablets must be given whole and should not be broken. The granules in sachets can be mixed with food or water.

Please refer to your pack and veterinary guidance for the amount to feed to your pet.

Weight Recommendation
Under 5kg 1 Small Breed
5-10kg 2 Small Breed
11-20kg 1 Medium Breed
21-30kg 2 Medium Breed
31-40kg 2 Large Breed
41-50kg 3 Large Breed


  • S-adenosyl L-methionine (SAMe) – the S,S-SAMe isomer is included in Samylin, which is the active form and is integral to correct hepatic function. It is enteric coated in Samylin to ensure stability and bioavailability
  • Silybin – the most active molecule found in milk thistle extract. The Silybin in Samylin is conjugated with phosphatidylcholine, which increases its bioavailability, facilitating its actions as a free radical scavenger in the liver
  • Vitamin E – a very potent antioxidant and lipid soluble vitamin, which can support the function of hepatocytes from within the lipid soluble environment of the cell membranes

All of our products are manufactured in Lytham, Lancashire to GMP Standard. To find out more about our manufacturing facility, click here.


Contact the vet you purchased Samylin from for guidance on the use of Samylin for your pet. They’ll be able to provide specialised advice for your pet due to the records they keep. If you are unable to get the information you need from your vet, or if you bought Samylin elsewhere, please contact us for assistance.

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Reviews (1)

Overall rating

By Amanda McKimmie
January 23, 2018


Sasha is a 9kg JRT born April 2003. In early Sept 2016 (13 yrs 5 mth) her tests and ultrasound revealed Liver Failure and reduced kidney failure with a 'probable' cause of cancer or cirrhosis with a life expectancy of 'borrowed time'. No biopsy was recommmended due to it being invasive and the outcome being unchanged. I had two options: A was to eat anything. B was a good diet and prayers! I researched solidly for a week and, with veterinary agreement, Sasha was fed Dechra Specific CKD/CKW and 2g of Samylin daily. Her Next review revealed her Kidneys were fully functional and a minute increase in her liver's ability to function! Fast forward passed Halloween, Guy Fawkes, My Birthday, Christmas, New Year, Valentine's Day, Shrove Tuesday AND SASHA'S 14th BIRTHDAY (Fanfare) it is now May 3rd 2017! Sasha manage to cover 3-3.5 miles of our Country Park 7 days a week AND swim for 5-10 minutes too! On her review last week she simply looked like a fit and healthy dog. She has a well priced Hepatic Diet she enjoys which reduces the work her liver has to do. The Samylin supports the work the liver has to do. With the liver functioning minimally it helps the heart and kidney from having to work harder. I believe that Samylin (along with her diet) are responsible for extending her life and I would recommend Samylin to every cat/dog with liver problems with veterinary advice - of course. Thank you for giving me six plus extra months with my bubby boo boo.